What is Cocaine

Cocaine is a powerfully addictive stimulant drug. For thousands of years, people in South America have chewed and ingested coca leaves (Erythroxylon coca), the source of cocaine, for their stimulant effects.^{1, 2} The purified chemical, cocaine hydrochloride, was isolated from the plant more than 100 years ago. In the early 1900s, purified cocaine was the main active ingredient in many tonics and elixirs developed to treat a wide variety of illnesses and was even an ingredient in the early formulations of Coca-Cola^®. Before the development of synthetic local anesthetic, surgeons used cocaine to block pain.¹ However, research has since shown that cocaine is a powerfully addictive substance that can alter brain structure and function if used repeatedly.

Uses of Cocaine

• Medical:

  Topical cocaine can be used as a local numbing agent to help with painful procedures in the mouth or nose.^[34] Cocaine may be used for nasal and lacrimal duct surgery. The major disadvantages of this use are cocaine’s potential for cardiovascular toxicity, glaucoma, and pupil dilation.^[34] Medicinal use of cocaine has decreased as other synthetic local anesthetics such as benzocaine, proparacaine, lidocaine, and tetracaine are now used more often

• Recreational:

  Cocaine is a nervous system stimulant. Its effects can last from 15 minutes to an hour. The duration of cocaine’s effects depends on the amount taken and the route of administration. Cocaine can be in the form of fine white powder, bitter to the taste. Crack cocaine is a smokeable form of cocaine made into small “rocks” by processing cocaine with sodium bicarbonate (baking soda) and water. Crack cocaine is referred to as “crack” because of the crackling sounds it makes when heated.

  Cocaine use leads to increases in alertness, feelings of well-being and euphoria, increased energy and motor activity, and increased feelings of competence and sexuality.

  Analysis of the correlation between the use of 18 various psychoactive substances shows that cocaine use correlates with other “party drugs” (such as ecstasy or amphetamines), as well as with heroin and benzodiazepines use, and can be considered as a bridge between the use of different groups of drugs.

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